Funct. Mater. 2020; 27 (1): 6-11.

doi:https://doi.org/10.15407/fm27.01.6

Improving ·OH scavenging properties of nanoceria by doping and pre-irradiation

V.V.Seminko, P.O.Maksimchuk, O.O.Sedyh, A.V.Aslanov, Yu.V.Malyukin

Institute for Scintillation Materials, STC "Institute for Single Crystals", National Academy of Sciences of Ukraine, 60 Nauky Ave., 61072 Kharkiv, Ukraine

Abstract: 

Hydroxyl radicals (·OH) are usually considered as the most dangerous type of reactive oxygen species formed inside the living cells that leads to increasing demand for antioxidant nanomaterials able to effective ·OH elimination. Nanoceria (CeO2-x) has recommended itself as the one of the most potent ·OH scavengers due to high content of Ce3+ ions and easy Ce3+↔Ce4+ switching making possible effective redox cycling. In the paper the direct connection between Ce3+ content and ·OH scavenging ability is shown. Doping of nanoceria by non-isovalent ions (Y3+) or by ions with smaller ionic radius (Zr4+) leads to increase of both Ce3+ content and antioxidant activity of nanoparticles. The same increase of ·OH scavenging ability is observed at pre-irradiation of nanoceria (λ = 325 nm) which is accompanied by transfer of the part of Ce4+ ions to Ce3+ ones. The observed effects are caused by formation of additional oxygen vacancies at doping or pre-irradiation providing increase in the number of sites (Ce3+-Ov-Ce3+ or Ce3+-Ov-RE3+) for ·OH scavenging.

Keywords: 
nanoceria, hydroxyl radicals, luminescence, pre-irradiation.

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References: 

 1. B.Halliwell, J.M.C.Gutteridge, Free Radicals in Biology and Medicine, Oxford University Press, Oxford (2015). https://doi.org/10.1093/acprof:oso/9780198717478.001.0001

 
2. S.G.Rhee, Experim. Mol. Medicine, 31, 53 (1999).
 
3. J.R.Stone, S.Yang, Antioxidants & Redox Signaling, 8, 243 (2006).
 
4. J.Cadet, T.Delatour, T.Douki et al,, Mutation Res./Fundament. Molecular Mechan. Mutagenesis, 424, 9 (1999).
 
5. B.Halliwell, J.M.C.Gutteridge, FEBS Lett., 307, 108 (1992).
 
6. B.A.Rzigalinski, Techn. Cancer Res. Treat., 4, 651 (2005).
 
7. E.G.Heckert, A.S.Karakoti, S.Seal et al., Biomaterials, 29, 2705 (2008).
 
8. T.Pirmohamed, J.M.Dowding, S.Singh et al., Chem. Commun., 46, 2736 (2010).
 
9. Y.Xue, Q.Luan, D.Yang et al., J. Phys. Chem. C, 115, 4433 (2011).
 
10. M.Lu, Y.Zhang, Y.Wang et al., ACS Appl. Mater. Interfaces, 8, 23580 (2016).
 
11. M.Dudek, J.Molenda, Mater. Sci.-Poland, 24, 45 (2006).
 
12. G.Balducci, J.Kaspar, P.Fornasiero et al. The J. Phys. Chem. B, 102, 557 (1998).
 
13. T.Montini, M.Melchionna, M.Monai, P.Fornasiero, Chem. Rev., 116, 5987 (2016).
 
14. V.Seminko, A.Masalov, P.Maksimchuk et al., Nanomaterials for Security, 149 (2016).
 
15. Y.Malyukin, V.Seminko, P.Maksimchuk et al., Opt.l Mater., 85, 303 (2018).
 
16. V.Seminko, P.Maksimchuk, G.Grygorova et al., J. Phys. Chem. C, 123, 20675 (2019).
 
17. E.N.Okrushko, V.V.Seminko, P.O.Maksimuchuk et al., Low Temper. Phys., 43, 636 (2017).
 
18. V.K.Klochkov, Yu.V.Malyukin, G.V.Grygorova et al., J. Photochem. Photobiol A: Chemistry, 364, 282 (2018).
 
19. V.Seminko, P.Maksimchuk, O.Avrunin et al., Phys. Status Solidi (B). DOI: 10.1002/pssb.201900325 (2019).
 
20. B.Herschend, M.Baudin, K.Hermansson, Surf. Sci., 173. 599 (2005).
 
21. N.V.Skorodumova, S.I.Simak, B.I.Lundqvist et al., Phys. Rev.w Lett., 89, 166601 (2002).
 
22. Y.Malyukin, P.Maksimchuk, V.Seminko et al., J. Phys. Chem. C, 122, 16406 (2018).

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